Call for Proposals: Generative-AI based Agents to Revolutionize Medical Diagnosis and Treatment of Cancer
Application Deadline:
29 October 2025
About Organisation
The European Commission (EC) is a vital institution of the European Union responsible for implementing decisions, managing day-to-day operations, and upholding EU treaties. It plays a pivotal role in advancing research, innovation, and development across diverse sectors to address global challenges. Through various funding programs like Horizon Europe, the EC fosters scientific research, technological advancement, and sustainable development. Horizon Europe, the EU’s flagship research and innovation program, emphasizes tackling pressing societal issues, fostering digital transformation, and supporting high-impact scientific breakthroughs. By promoting collaborative research and innovation, the EC empowers organizations, academic institutions, and industries to develop transformative solutions for complex problems. The Commission’s initiatives are designed to encourage cross-border partnerships and enhance the EU’s position as a leader in scientific research and global innovation. With significant investments in emerging technologies, health, climate action, and digitalization, the EC aims to improve societal well-being and economic growth. Through its structured and transparent funding mechanisms, the EC ensures that groundbreaking projects, particularly those in early experimental phases, receive adequate support to translate ideas into impactful real-world solutions.
About the Grant
The European Commission is inviting proposals for its Pathfinder Challenge on Generative-AI (GenAI) agents to revolutionize cancer diagnosis and treatment. This grant focuses on developing interactive GenAI-based autonomous agents that enhance clinical decision-making and improve patient care by integrating multidimensional and multimodal health data. Proposals must target one of eight specified cancers, including breast, lung, brain, or colorectal cancer, and address both technological advancements and clinical applications. The technological area emphasizes the development of innovative GenAI tools for data integration, medical data augmentation, and dynamic medical knowledge representation. The clinical area focuses on predictive diagnosis and personalized treatment planning. This initiative aims to create holistic AI-powered systems that overcome the challenges of data fragmentation, limited interpretability of AI models, and inefficiencies in healthcare delivery. Projects are expected to advance the use of synthetic medical data, develop advanced algorithms, and enable early detection and personalized therapy to improve patient outcomes. The total budget for 2025 is €120 million, with individual contributions ranging between €500,000 and €4 million. By funding early-stage, high-risk, and groundbreaking research, the EC aims to accelerate innovation in cancer care through advanced AI technologies.
Who can Apply?
The grant is open to all legal entities, including organizations, research institutions, startups, universities, and international organizations, regardless of their location, provided they meet the conditions specified under Horizon Europe regulations. A legal entity is defined as any natural or legal person with recognized legal personality under national, EU, or international law, capable of exercising rights and obligations in its own name. Entities without legal personality may also participate if they meet the requirements outlined in Article 200(2)(c) of the Financial Regulation. To qualify for funding, applicants must be established in eligible countries, including all EU Member States such as France, Germany, Spain, and Italy, as well as the associated countries under Horizon Europe, including the United Kingdom, Norway, Israel, Türkiye, and Ukraine. Overseas Countries and Territories linked to EU Member States, such as Greenland, French Polynesia, and Aruba, are also eligible. While entities from non-associated third countries may participate, their funding eligibility will depend on the specific conditions of the call. Applicants must demonstrate expertise in GenAI, healthcare innovation, medical imaging, or related fields. Collaborative, multidisciplinary proposals are encouraged to maximize innovation and impact in addressing cancer diagnosis and treatment challenges.
How to Apply?
Applicants must prepare a detailed proposal outlining their project’s objectives, methodology, and expected impact. The proposal should focus on one eligible cancer type and cover both technological and clinical areas as defined in the grant guidelines. Submissions are to be made through the designated Horizon Europe application platform, following the required format, including technical and financial details. Collaborative and interdisciplinary teams are strongly encouraged
Application Deadline
The deadline for submitting proposals for the Generative-AI Cancer Diagnosis and Treatment Pathfinder Challenge is 29 October 2025. Early submission is recommended to avoid technical issues and ensure completeness.
Last Date To Apply
Applicants must ensure that their final proposals are submitted no later than 29 October 2025, 17:00 CET, as late submissions will not be considered for evaluation or funding.
Grant Amount
The total budget allocated for this grant in 2025 is €120 million, with individual project funding ranging between €500,000 and €4 million, depending on project scope and objectives.
Last Date To Apply
For more information, please visit the grant website here.
